(SOME SPOILERS FOLLOW) After making my way back through Virmire and going through the Citadel for one last time, I finished all of my remaining side-quests (including the resource gathering ones), clearing the way for a straight run through Ilos to the end of the game tomorrow. Deciding on who to save on Virmire was a tough decision, since my love interest in this game is Liara and because I don't have access to my very first playthrough at the moment to fall back on (I originally played Mass Effect when it was first released on XBox 360). Ultimately, I decided to save Kaiden, my Shepard saving Lt. Alenko and Captain Kirrahe's team, who were together at the time. I'm still not sure if going back to the nuke (regardless of who's arming it) is one of the deciding factors when figuring out if Captain Kirrahe's team survives, or if they can still make it depending on your prior actions.
Role-playing/Third-Person 3D Action RPG